高血压 treatment in pregnancy is safe and could reduce mother's risks

Treating high blood pressure during pregnancy is safe and may be helpful at lower thresholds than previously thought, 一份新的科学报告称.

"For decades, the benefits of blood pressure treatment for pregnant women were unclear," Dr. Vesna D. Garovic在线上电子游戏飞禽走兽发布会上说. 她领导了一个专家委员会，审查和分析现有的研究. "And there were concerns about fetal well-being from exposure to antihypertensive medications."

但周三发表的这份报告是一份报告 科学声明 来自美国心脏协会的《线上娱乐电子游戏网站》杂志, said treatment may reduce a woman's risk for severe high blood pressure without endangering her child.

高血压, 或高血压, during pregnancy is a major cause of complications and death for mothers and their babies, 它还增加了女性患心血管疾病的短期和长期风险. 它还会增加早产和低出生体重的风险.

在高收入国家中，美国经济增长最快.S. has one of the highest maternal mortality rates for high blood pressure-related problems. 心血管病, 包括中风和心力衰竭, 现在占美国孕产妇死亡总数的一半.S., where pregnancy-related stroke hospitalizations increased more than 60% from 1994 to 2011.

In the U.S., high blood pressure during pregnancy disproportionately affects women who are Black, 美国印第安人或阿拉斯加原住民.

“鉴于怀孕期间高血压病例的增加, 还有高血压相关的并发症, 这一问题已成为一场公共卫生危机, 尤其是来自不同种族和民族背景的妇女,加洛维奇说。, 罗切斯特市梅奥诊所的医学教授, Minnesota.

A 科学声明 is an expert analysis of current research and may inform future clinical practice guidelines. 这篇文章是由妇产科专家写的, 母胎医学, cardiology, nephrology, 高血压和内科.

妊娠期高血压是最常见的 是全世界孕产妇死亡的第二大原因. Severe cases are associated with increased risks of heart-related complications for mothers both immediately after delivery and for years later.

Because of concerns about how medications may affect the fetus, treatment guidelines vary.

Since 2017, the AHA and the American College of Cardiology have defined high blood pressure in the general population as a systolic (top) reading of at least 130 mmHg or a diastolic (bottom) reading of at least 80 mmHg.

Most guidelines worldwide define high blood pressure during pregnancy as a reading of 140/90. In the U.S., the American College of Obstetricians and Gynecologists recommends starting treatment at 160/110. 其他指南建议从140/90开始治疗.

The statement said the latest research indicates use of blood pressure-lowering medicine during pregnancy does not appear to harm fetal development. And preventing high blood pressure during pregnancy supports maternal health both during and after pregnancy. Women who have hypertension during pregnancy are more likely to develop sustained high blood pressure after pregnancy at a higher rate compared to those whose blood pressure was normal during pregnancy.

"Future clinical trials are needed to address questions about when to begin treatment for high blood pressure during pregnancy,加洛维奇说. But, she said, it was "reassuring" that the statement's comprehensive review of research showed "emerging evidence that treating high blood pressure during pregnancy is safe and effective and may be beneficial at lower thresholds than previously thought."

Reducing severe high blood pressure may be particularly important in communities that lack resources and expertise to respond to hypertension emergencies, 声明说.

It also reinforces recent research that suggests lifestyle changes before and during pregnancy can improve maternal and fetal outcomes. For example, dietary changes before and during pregnancy can limit weight gain and improve pregnancy outcomes. And exercise during pregnancy may reduce the risk of gestational hypertension by about 30% and of preeclampsia by about 40%.

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